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Anti-Human CD289 (TLR9) PE

Anti-Human CD289 (TLR9) PE

Item no.	31011-60-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies Flow Cytometry Primary Antibodies By Organ Pancreatic Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	72-1665
Specific against	Human (Homo sapiens)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	PE
Citations	Latz, E., Schoenemeyer, A., Visintin, A., Fitzgerald, K. A., Monks, B. G., Knetter, C. F., ... & Golenbock, D. T. (2004). TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nature immunology, 5(2), 190-198. Leifer, C. A., Kennedy, M. N., Mazzoni, A., Lee, C., Kruhlak, M. J., & Segal, D. M. (2004). TLR9 is localized in the endoplasmic reticulum prior to stimulation.The Journal of Immunology, 173(2), 1179-1183. Jazsef, L., Khreiss, T., El Kebir, D., & Filep, J. G. (2006). Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. The Journal of immunology, 176(2), 1195-1202.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 72-1665 monoclonal antibody specifically reacts with CD289, also known as human toll-like receptor 9 (TLR9). CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system’s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

31011-60-100-datasheet.pdf

31011-60-100-safety-datasheet.pdf