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Anti-Human c-Myc Purified

Anti-Human c-Myc Purified

Item no.	72211-20-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Flow Cytometry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Bladder Cancer
Type	Antibody
Format	Purified
Applications	WB, FC, IF, IP, ICC
Clone	9E10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Campbell, A. M., Kessler, P. D., & Fambrough, D. M. (1992). The alternative carboxyl termini of avian cardiac and brain sarcoplasmic reticulum/endoplasmic reticulum Ca (2+)-ATPases are on opposite sides of the membrane. Journal of Biological Chemistry, 267(13), 9321-9325. Hilpert, K., Hansen, G., Wessner, H., Küttner, G., Welfle, K., Seifert, M., & Hähne, W. (2001). Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose. Protein engineering, 14(10), 803-806. Krauay, N., Wessner, H., Welfle, K., Welfle, H., Scholz, C., Seifert, M., ... & Hähne, W. (2008). The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops. Proteins: Structure, Function, and Bioinformatics, 73(3), 552-565.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 9E10 monoclonal antibody specifically reacts with the human c-Myc p67 molecule, a proto-oncogene from the Myc family, which is important in transformation, proliferation, and differentiation. This gene is expressed during embryonic development, in some adult tissues, and is amplified in some tumors. Inside the cell, the gene is localized in the nucleus or cytoplasm. C-Myc is characterized by a Leucine zipper, a basic region, and a helix-loop-helix, which allow the formation of a heterodimer Myc-Max that binds to DNA, and activates the transcription. The 9E10 antibody recognizes the human c-Myc and can be used for Myc-tagged protein detection. It was obtained by using synthetic peptide similar to the terminal domain of human c-Myc as an immunogen.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Format	Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/23/2025

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