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Anti-Human IL-4 SAFIRE Purified

Anti-Human IL-4 SAFIRE Purified

Item no.	81121-25-500
Manufacturer	BioGems
Amount	500 ug
Category	Neuroscience Neuroinflammation Antibodies Cell Biology Cell Culture Cytokines Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Clone	MP4-25D2
Specific against	Human (Homo sapiens)
Host	Rat
Isotype	IgG1 Kappa
Citations	Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.Immunological reviews, 127(1), 5-24. Chretien, I., Van Kimmenade, A., Pearce, M. K., Banchereau, J., & Abrams, J. S. (1989). Development of polyclonal and monoclonal antibodies for immunoassay and neutralization of human interleukin-4. Journal of immunological methods, 117(1), 67-81. Jung, T., Schauer, U., Rieger, C., Wagner, K., Einsle, K., Neumann, C., & Heusser, C. (1995). Interleukin-4 and interleukin-5 are rarely co-expressed by human T cells. European journal of immunology, 25(8), 2413-2416.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The MP4-25D2 monoclonal antibody specifically reacts with human Interleukin-4 (IL-4), expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The MP4-25D2 is a neutralizing antibody and is reported to be cross-reactive with rhesus monkeys.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Adaptive Immunity, Innate Immunity, Cytokines & Growth Factors
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

81121-25-500-datasheet.pdf

81121-25-500-safety-datasheet.pdf