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Anti-Human/Mouse CD62P (P-Selectin) SAFIRE Purified

Anti-Human/Mouse CD62P (P-Selectin) SAFIRE Purified

Item no.	04722-25-50
Manufacturer	BioGems
Amount	50 ug
Category	Neuroscience Neural Lineage Markers Neural Signaling Neural Adhesion Molecules Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE (Functional)
Applications	FC
Clone	Psel.KO2.12
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
Citations	Massaguer, A., Engel, P., Perez-del-Pulgar, S., Bosch, J., & Pizcueta, P. (2000). Production and characterization of monoclonal antibodies against conserved epitopes of P-selectin (CD62P). Tissue antigens, 56(2), 117-128. Kansas, G. S. (1996). Selectins and their ligands: current concepts and controversies. Blood, 88(9), 3259-3287. Bullard, D. C., Kunkel, E. J., Kubo, H., Hicks, M. J., Lorenzo, I., Doyle, N. A., ... & Beaudet, A. L. (1996). Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. The Journal of experimental medicine, 183(5), 2329-2336.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The Psel.KO2.12 monoclonal antibody specifically reacts with mouse CD62P (P-Selectin), a 140 kDA type I transmembrane glycoprotein also known as granule membrane protein 140 (GMP-140). Upon activation it is quickly transported to the plasma membrane from the alpha-granules of platelets and WEibel-Palade bodies of endothelial cells. It is essential to the functions of cell adhesion during inflammatory reactions and in the interaction of platelets with monocytes and neutrophils. The Psel.KO2.12 antibody binds to an epitope common to several species including mouse, human, and rat.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Adaptive Immunity, Angiogenesis
Format	SAFIRE (Functional)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

04722-25-50-datasheet.pdf

04722-25-50-safety-datasheet.pdf