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Anti-Human CD27 SAFIRE Purified

Anti-Human CD27 SAFIRE Purified

Item no.	09331-25-500
Manufacturer	BioGems
Amount	500 ug
Category	Neuroscience Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	LG.7F9
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Hamster - Armenian
Isotype	IgG
Citations	Tesselaar, K., Xiao, Y., Arens, R., van Schijndel, G. M., Schuurhuis, D. H., Mebius, R. E., ... & van Lier, R. A. (2003). Expression of the murine CD27 ligand CD70 in vitro and in vivo. The journal of immunology, 170(1), 33-40. Lee, E. M., Hurh, S., Cho, B., Oh, K. H., Kim, S. U., Surh, C. D., ... & Ahn, C. (2013). CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T cell death. Stem cell research & therapy, 4(3), 56. Gravestein, L. A., Nieland, J. D., Kruisbeek, A. M., & Borst, J. (1995). Novel mAbs reveal potent co-stimulatory activity of murine CD27. International immunology, 7(4), 551-557.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The LG.7F9 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.7F9 antibody is cross-reactive human, mouse, and rat CD27.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Adaptive Immunity, Apoptosis
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

09331-25-500-datasheet.pdf

09331-25-500-safety-datasheet.pdf