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Anti-Human/Mouse MCP-1 (CCL2) SAFIRE Purified

Anti-Human/Mouse MCP-1 (CCL2) SAFIRE Purified

Item no.	80111-25-500
Manufacturer	BioGems
Amount	500 ug
Category	Neuroscience Neuroinflammation Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	2H5
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Hamster - Armenian
Isotype	IgG
Citations	Luo, Y., Laning, J., Hayashi, M., Hancock, P. R., Rollins, B., & Dorf, M. E. (1994). Serologic analysis of the mouse beta chemokine JE/monocyte chemoattractant protein-1. The Journal of immunology, 153(8), 3708-3716. Bost, K. L., Bento, J. L., Petty, C. C., Schrum, L. W., Hudson, M. C., & Marriott, I. (2001). Monocyte chemoattractant protein-1 expression by osteoblasts following infection with Staphylococcus aureus or Salmonella.Journal of Interferon & Cytokine Research, 21(5), 297-304. Taal, M. W., Chertow, G. M., Rennke, H. G., Gurnani, A., Jiang, T., Shahsafaei, A., ... & Mackenzie, H. S. (2001). Mechanisms underlying renoprotection during renin-angiotensin system blockade. American Journal of Physiology-Renal Physiology, 280(2), F343-F355.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 2H5 monoclonal antibody specifically reacts with mouse, rat, human MCP-1 (Monocyte Chemoattractant Protein-1), also known as CCL2 and MCAF (Monocyte Chemotactic and Activating Factor). MCP-1 is a C-C (beta) chemokine that regulates cytokine production in monocytes and the expression of adhesion molecules. The 2h5 antibody can neutralize the bioactivity of recombinant or natural MCP-1.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Chemotaxis, Angiogenesis
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

80111-25-500-datasheet.pdf

80111-25-500-safety-datasheet.pdf