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Anti-Mouse CD20 SAFIRE Purified

Anti-Mouse CD20 SAFIRE Purified

Item no.	02312-25-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Myeloma Flow Cytometry Primary Antibodies By Organ Bladder Cancer Gastric Cancer Lymphatic System Cancer
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	AISB12
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a
Citations	Uchida, J., Hamaguchi, Y., Oliver, J. A., Ravetch, J. V., Poe, J. C., Haas, K. M., & Tedder, T. F. (2004). The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-"dependent mechanisms during anti-CD20 antibody immunotherapy. The Journal of experimental medicine,199(12), 1659-1669. Uchida, J., Lee, Y., Hasegawa, M., Liang, Y., Bradney, A., Oliver, J. A., ... & Tedder, T. F. (2004). Mouse CD20 expression and function. International immunology, 16(1), 119-129. Qian, J., Zheng, Y., Zheng, C., Wang, L., Qin, H., Hong, S., ... & Yi, Q. (2012). Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma. Blood, 119(1), 161-169.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Adaptive Immunity
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

02312-25-100-datasheet.pdf

02312-25-100-safety-datasheet.pdf