Comparison

Anti-Mouse CD14 FITC

Item no. 06212-50-50
Manufacturer BioGems
Amount 50 ug
Category
Type Antibody
Format FITC
Applications FC
Clone Sa2-8
Specific against Mouse (Murine, Mus musculus)
Host Rat
Isotype IgG2a Kappa
Conjugate/Tag FITC
Citations Akashi, S., Saitoh, S. I., Wakabayashi, Y., Kikuchi, T., Takamura, N., Nagai, Y., ... & Miyake, K. (2003). Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 Higher Affinity than That with MD-2 or CD14. The Journal of experimental medicine, 198(7), 1035-1042.
Oliva, C., Turnbough, C. L., & Kearney, J. F. (2009). CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages. Proceedings of the National Academy of Sciences, 106(33), 13957-13962.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Description
The Sa2-8 monoclonal antibody specifically reacts with mouse CD14, a cell surface anchored glycoprotein that is primarily expressed on macrophages and is secreted in certain conditions. CD14 associates with LPS and LBP to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The Sa2-8 antibody exhibits a weak antagonistic activate in relation to TNF alpha production and NF-kappa B activation.
Storage Temperature
4C
Formulation
Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation
The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest
Innate Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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