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Anti-Mouse CD48 PE

Anti-Mouse CD48 PE

Item no.	10512-60-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Breast Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	HM48-1
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Isotype	IgG
Conjugate/Tag	PE
Citations	Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... & Yagita, H. (1992). CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. The Journal of experimental medicine, 176(5), 1241-1249. Qin, L., Chavin, K. D., Lin, J., Yagita, H., & Bromberg, J. S. (1994). Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival. The Journal of experimental medicine, 179(1), 341-346. Chavin, K. D., Qin, L., Lin, J., Woodward, J., Baliga, P., Kato, K., ... & Bromberg, J. S. (1994). Anti-CD48 (murine CD2 ligand) mAbs suppress cell mediated immunity in vivo. International immunology, 6(5), 701-709.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The HM48-1 monoclonal antibody specifically reacts with mouse CD48, a GPI-anchored molecule in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells. The utilization of the HM48-1 antibody has been reported to prolong cardiac allografts survival in in vivo studies. The antibody blocks the interaction of CD2 and CD244, inhibits CTL priming, and blocks the binding of soluble CD2 to CD48 expressing cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity, Stem Cell Research, Adaptive Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

10512-60-100-datasheet.pdf

10512-60-100-safety-datasheet.pdf