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Anti-mouse CD49d (Integrin alpha 4) SAFIRE Purified

Anti-mouse CD49d (Integrin alpha 4) SAFIRE Purified

Item no.	11522-25-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Neuroinflammation Protein Aggregation, Clearance & Misfolding Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Primary Antibodies By Organ Renal Cancer
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	R1-2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Citations	Baron, J. L., Reich, E. P., Visintin, I., & Janeway Jr, C. A. (1994). The pathogenesis of adoptive murine autoimmune diabetes requires an interaction between alpha 4-integrins and vascular cell adhesion molecule-1. Journal of Clinical Investigation, 93(4), 1700. Chisholm, P. L., Williams, C. A., & Lobb, R. R. (1993). Monoclonal antibodies to the integrin α-4 subunit inhibit the murine contact hypersensitivity response.European journal of immunology, 23(3), 682-688. Holzmann, B., McIntyre, B. W., & Weissman, I. L. (1989). Identification of a murine Peyer's patch-"specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α. Cell, 56(1), 37-46.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The R1-2 monoclonal antibody specifically reacts with mouse CD49d (integrin alpha 4), which forms the VLA-4 complex with CD29 (integrin beta 1). VLA-4 is expressed on thymocytes, monocytes, and a subset of peripheral lymphocytes. It is the receptor for fibronectin and CD106 (VCAM-1). CD49d also forms a receptor for mucosal vascular addressin (MAdCAM-1) with integrin beta 7.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Adaptive Immunity, Angiogenesis
Format	SAFIRE Purified

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11522-25-100-datasheet.pdf

11522-25-100-safety-datasheet.pdf