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Anti-Mouse CD49b (Integrin alpha 2) FITC 500 ug

Anti-Mouse CD49b (Integrin alpha 2) FITC 500 ug

Item no.	11532-50-500
Manufacturer	BioGems
Amount	500 ug
Category	Neuroscience Neural Adhesion Molecules Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	FITC
Applications	FC
Clone	DX5
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgM Kappa
Conjugate/Tag	FITC
Citations	Arase, H., Saito, T., Phillips, J. H., & Lanier, L. L. (2001). Cutting edge: the mouse NK cell-associated antigen recognized by DX5 moncoclonal antibody is CD49b (α2 integrin, very late antigen-2). The Journal of Immunology, 167(3), 1141-1144. Fernandez, N. C., Lozier, A., Flament, C., Ricciardi-Castagnoli, P., Bellet, D., Suter, M., ... & Zitvogel, L. (1999). Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.Nature medicine, 5(4), 405-411. Gadue, P., & Stein, P. L. (2002). NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation. The Journal of Immunology, 169(5), 2397-2406.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The DX5 monoclonal antibody specifically binds with mouse CD49b, a 150kDA integrin alpha chain that forms the VLA-2 complex with CD29 (integrin beta 1). CD49b is expressed on most mouse NK cells, platelets, NKT cells, and a subset of T cells. The DX5 antibody has been reported to been used to distinguish functional subset of NK cells, as it can be used to identify mouse NK cells that do not exhibit the NK1.1 antigen.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Angiogenesis, Innate Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

11532-50-500-datasheet.pdf

11532-50-500-safety-datasheet.pdf