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Anti-Mouse CD140a (PDGF Receptor a) SAFIRE Purified

Anti-Mouse CD140a (PDGF Receptor a) SAFIRE Purified

Item no.	12512-25-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies By Organ Colorectal Cancer
Type	Antibody
Format	SAFIRE (Functional)
Applications	WB, FC, IHC
Clone	APA5
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Citations	Fruttiger, M., Calver, A. R., Krüger, W. H., Mudhar, H. S., Michalovich, D., Takakura, N., ... & Richardson, W. D. (1996). PDGF mediates a neuron-"astrocyte interaction in the developing retina. Neuron, 17(6), 1117-1131. Takakura, N., Yoshida, H., Ogura, Y., Kataoka, H., Nishikawa, S., & Nishikawa, S. I. (1997). PDGFRα expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFRα antibody APA5. Journal of Histochemistry & Cytochemistry, 45(6), 883-893. Takakura, N., Yoshida, H., Kunisada, T., Nishikawa, S., & Nishikawa, S. I. (1996). Involvement of Platelet-Derived Growth Factor Receptor-&agr, in Hair Canal Formation. Journal of investigative dermatology, 107(5), 770-777.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The APA5 monoclonal antibody specifically binds to the mouse CD140a molecule, otherwise known as the Platelet-Derived Growth Factor (PDGF) Receptor alpha chain. CD140a is a receptor tyrosine kinase expressed on embryonic tissues and adult mesenchymal-derived cells. It binds to PDGF A and B chains and is reported to be involved with wound healing and exhibits chemo-attractant properties. The APA5 antibody blocks the binding of PDGF-AA to the PDGF receptor.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Stem Cell Research
Format	SAFIRE (Functional)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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12512-25-100-datasheet.pdf

12512-25-100-safety-datasheet.pdf