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Anti-Mouse CD140b (PDGF Receptor b) SAFIRE Purified

Anti-Mouse CD140b (PDGF Receptor b) SAFIRE Purified

Item no.	12522-25-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Flow Cytometry Primary Antibodies By Organ Skin Cancer
Type	Antibody
Format	SAFIRE (Functional)
Applications	FC
Clone	APB5
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Citations	Jo, N., Mailhos, C., Ju, M., Cheung, E., Bradley, J., Nishijima, K., ... & Shima, D. T. (2006). Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization. The American journal of pathology,168(6), 2036-2053. Sano, H., Sudo, T., Yokode, M., Murayama, T., Kataoka, H., Takakura, N., ... & Kita, T. (2001). Functional blockade of platelet-derived growth factor receptor-β but not of receptor-α prevents vascular smooth muscle cell accumulation in fibrous cap lesions in apolipoprotein E-"deficient mice. Circulation, 103(24), 2955-2960. Soriano, P. (1994). Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. Genes & development, 8(16), 1888-1896.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The APB5 monoclonal antibody specifically binds to the mouse CD140b molecule, otherwise known as the Platelet-Derived Growth Factor (PDGF) Receptor beta chain. CD140b is a receptor tyrosine kinase expressed on embryonic tissue and adult mesenchymal-derived cells. The APB5 antibody is reported to block the binding of PDGF-BB to the PDGF receptor.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Stem Cell Research
Format	SAFIRE (Functional)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

12522-25-100-datasheet.pdf

12522-25-100-safety-datasheet.pdf