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Anti-Mouse CD180 (RP-105) SAFIRE Purified 50ug

Anti-Mouse CD180 (RP-105) SAFIRE Purified 50ug

Item no.	12912-25-50
Manufacturer	BioGems
Amount	50 ug
Category	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE (Functional)
Applications	FC
Clone	RP/14
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Citations	Miyake, K., Shimazu, R., Kondo, J., Niki, T., Akashi, S., Ogata, H., ... & Kimoto, M. (1998). Mouse MD-1, a molecule that is physically associated with RP105 and positively regulates its expression. The Journal of Immunology,161(3), 1348-1353. Miyake, K., Yamashita, Y., Ogata, M., Sudo, T., & Kimoto, M. (1995). RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. The Journal of Immunology, 154(7), 3333-3340. Chan, V. W., Mecklenbräuker, I., Su, I. H., Texido, G., Leitges, M., Carsetti, R., ... & Tarakhovsky, A. (1998). The molecular mechanism of B cell activation by toll-like receptor protein RP-105. The Journal of experimental medicine,188(1), 93-101.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The RP/14 monoclonal antibody binds to mouse CD180, a 105kDA cell surface molecule consisting of extracellular leucine rich repeats (LCC) and a short cytoplasmic tail also known as Bgp-95 and RP105. CD180 is expressed on B cells, dendritic cells, monocytes, and macrophages. It forms a cell surface receptor complex with MD-1 and with TLR4 is involved with the recognition of bacterial lipopolysaccharide (LPS)
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Innate Immunity, Apoptosis
Format	SAFIRE (Functional)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

12912-25-50-datasheet.pdf

12912-25-50-safety-datasheet.pdf