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Anti-Mouse CD122 SAFIRE Purified

Anti-Mouse CD122 SAFIRE Purified

Item no.	14312-25-100
Manufacturer	BioGems
Amount	100 ug
Category	Neuroscience Neural Lineage Markers Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE (Functional)
Applications	FC
Clone	TM-beta1
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b
Citations	Alleva, D. G., Kaser, S. B., Monroy, M. A., Fenton, M. J., & Beller, D. I. (1997). IL-15 functions as a potent autocrine regulator of macrophage proinflammatory cytokine production: evidence for differential receptor subunit utilization associated with stimulation or inhibition. The Journal of Immunology,159(6), 2941-2951. Suzuki, H., Kundig, T. M., Furlonger, C., Wakeham, A., Timms, E., Matsuyama, T., ... & Griesser, H. (1995). Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science, 268(5216), 1472-1476. Takeuchi, Y., Tanaka, T., Hamamura, K., Sugimoto, T., Miyasaka, M., Yagita, H., & Okumura, K. (1992). Expression and role of interleukin-2 receptor β chain on CD4-CD8+ T cell receptor αβ+ cells. European journal of immunology,22(11), 2929-2935.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The TM-beta1 monoclonal antibody specifically reacts with mouse CD122, a beta chain shared by the IL-2 and IL-15 receptors. It is expressed by B cells, T cells, and NK cells and can be used as a marker for NK-cell progenitors. CD122 forms complexes involved in immunoregulation and signal transduction. The TM-beta1 antibody is reported to block the binding of IL-2 and IL-15 to the IL-2 beta receptor.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	T Cells, NK and NKT Cells, B Cells
Format	SAFIRE (Functional)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

14312-25-100-datasheet.pdf

14312-25-100-safety-datasheet.pdf