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Anti-Mouse CD103 (Integrin alpha E) SAFIRE Purified

Anti-Mouse CD103 (Integrin alpha E) SAFIRE Purified

Item no.	15112-25-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Neural Adhesion Molecules Antibodies By Cell Type Hematology Leukemia Cell Biology Cell Movement Cell Adhesion Flow Cytometry Primary Antibodies By Organ Renal Cancer
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	2E7
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Isotype	IgG
Citations	Hadley, G. A., Bartlett, S. T., Via, C. S., Rostapshova, E. A., & Moainie, S. (1997). The epithelial cell-specific integrin, CD103 (alpha E integrin), defines a novel subset of alloreactive CD8+ CTL. The Journal of Immunology, 159(8), 3748-3756. Schän, M. P., Schän, M., Parker, C. M., & Williams, I. R. (2002). Dendritic Epidermal T Cells (DETC) are Diminished in Integrin &agr, E (CD103)-Deficient Mice. Journal of investigative dermatology, 119(1), 190-193. Zikri, N. N., Schumer, E., Wang, J. J., Gaughan, A., Hadley, G. A., & Moffatt-Bruce, S. D. (2010). Induction of CD4< sup>+</sup> CD25< sup>+</sup> T Regulatory Cells with CD103 Depletion. Journal of Surgical Research, 163(1), 162-168.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 2E7 monoclonal antibody specifically reacts with mouse CD103, a type I transmembrane glycoprotein in the integrin family that bind to E-cadherin. CD103 is expressed on intraepithelial lymphocyte T cells, peripheral regulatory T cells, lamina propria T cells, and a subset of dendritic cells. It is reported to be involved in T cell homing and immune system regulation.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Adaptive Immunity
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

15112-25-100-datasheet.pdf

15112-25-100-safety-datasheet.pdf