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Anti-Mouse CD184 (CXCR4) PE

Anti-Mouse CD184 (CXCR4) PE

Item no.	16912-60-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Flow Cytometry Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Pancreatic Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	2B11
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Conjugate/Tag	PE
Citations	Färster, R., Kremmer, E., Schubel, A., Breitfeld, D., Kleinschmidt, A., Nerl, C., ... & Lipp, M. (1998). Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation. The Journal of Immunology, 160(3), 1522-1531. Schabath, R., Müller, G., Schubel, A., Kremmer, E., Lipp, M., & Färster, R. (1999). The murine chemokine receptor CXCR4 is tightly regulated during T cell development and activation. Journal of leukocyte biology, 66(6), 996-1004. Gupta, S. K., Lysko, P. G., Pillarisetti, K., Ohlstein, E., & Stadel, J. M. (1998). Chemokine Receptors in Human Endothelial Cells FUNCTIONAL EXPRESSION OF CXCR4 AND ITS TRANSCRIPTIONAL REGULATION BY INFLAMMATORY CYTOKINES. Journal of Biological Chemistry, 273(7), 4282-4287.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1. The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Stem Cell Research, Cytokines & Growth Factors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

16912-60-100-datasheet.pdf

16912-60-100-safety-datasheet.pdf