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Anti-Mouse CD115 (CSF-1R) SAFIRE Purified

Anti-Mouse CD115 (CSF-1R) SAFIRE Purified

Item no.	17212-25-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Flow Cytometry Western Blot Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Applications	WB, FC
Clone	AFS98
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Citations	Murayama, T., Yokode, M., Kataoka, H., Imabayashi, T., Yoshida, H., Sano, H., ... & Kita, T. (1999). Intraperitoneal administration of anti-"c-fms monoclonal antibody prevents initial events of atherogenesis but does not reduce the size of advanced lesions in apolipoprotein E-"deficient mice. Circulation, 99(13), 1740-1746. Sudo, T., Nishikawa, S., Ogawa, M., Kataoka, H., Ohno, N., Izawa, A., & Hayashi, S. (1995). Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M. Oncogene, 11(12), 2469-2476. Yoshino, M., Yamazaki, H., Yoshida, H., Niida, S., Nishikawa, S. I., Ryoke, K., ... & Hayashi, S. I. (2003). Reduction of osteoclasts in a critical embryonic period is essential for inhibition of mouse tooth eruption. Journal of Bone and Mineral Research, 18(1), 108-116.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The AFS98 monoclonal antibody specifically reacts with the mouse CD115 molecule, a 150 kDa receptor for the colony stimulating factor (CSF-1) or macrophage CFS (M-CFS), expressed by some epithelial cells, monocytes, osteoclasts, and macrophages. The colony stimulating factor-1 regulates the proliferation and the differentiation of the monocytic lineage cells. The AFS98 antibody can be used to identify myeloid lineage cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µ g of the protein.
Research Interest	Innate Immunity, Angiogenesis
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

17212-25-100-datasheet.pdf

17212-25-100-safety-datasheet.pdf