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Anti-Mouse CD117 (c-Kit) PE

Anti-Mouse CD117 (c-Kit) PE

Item no.	19112-60-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Flow Cytometry Primary Antibodies By Organ Pancreatic Cancer Bone Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	ACK2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Conjugate/Tag	PE
Citations	Godfrey, D. I., Kennedy, J., Mombaerts, P., Tonegawa, S., & Zlotnik, A. (1994). Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8-thymocyte differentiation. The Journal of Immunology, 152(10), 4783-4792. Godfrey, D. I., Zlotnik, A. L. B. E. R. T., & Suda, T. A. K. A. S. H. I. (1992). Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. The Journal of Immunology, 149(7), 2281-2285. Feng, H., Sandlow, J. I., & Sandra, A. (1998). The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa. Molecular reproduction and development, 49(3), 317-326.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

19112-60-100-datasheet.pdf

19112-60-100-safety-datasheet.pdf