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Anti-Mouse CD252 (OX40L) Biotin25 ug

Anti-Mouse CD252 (OX40L) Biotin25 ug

Manufacturer	BioGems
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Flow Cytometry Primary Antibodies
Type	Antibody
Specific against	Mouse
Clone	RM134L
Isotype	IgG2b kappa
Format	Biotin
Applications	FC
Amount	25 ug
Host	Rat
Item no.	24611-30-25
Targets	CD134;;CD252
Conjugate/Tag	Biotin
eClass 6.1	32160702
eClass 9.0	32160702
Available
Description	The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells. On activated B cells it enhances immunoglobulin secretion and cell proliferation. CD252 is also known as the OX-40 ligand and interacts with the OX-40 antigen found on the surface of activated T cells. The RML134L is reported to block the costimulatory activity of OX-40L.
Research Interest	Adaptive Immunity
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted biotin was removed from the product.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
References	Stüber, E., Neurath, M., Calderhead, D., Perry Fell, H., & Strober, W. (1995). Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity, 2(5), 507-521. Akiba, H., Oshima, H., Takeda, K., Atsuta, M., Nakano, H., Nakajima, A., ... & Okumura, K. (1999). CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. The Journal of Immunology, 162(12), 7058-7066. Calderhead, D. M., Buhlmann, J. E., Van den Eertwegh, A. J., Claassen, E., Noelle, R. J., & Fell, H. P. (1993). Cloning of mouse Ox40: a T cell activation marker that may mediate TB cell interactions. The Journal of Immunology, 151(10), 5261-5271.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 ug

available

Delivery expected until 5/30/2024