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Anti-Mouse CD335 (NKp46) PE size 25 ug

Anti-Mouse CD335 (NKp46) PE size 25 ug

Item no.	37412-60-25
Manufacturer	BioGems
Amount	25 ug
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Pancreatic Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	29A1.4
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Conjugate/Tag	PE
Citations	Walzer, T., Blery, M., Chaix, J., Fuseri, N., Chasson, L., Robbins, S. H., ... & Vivier, E. (2007). Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. Proceedings of the National Academy of Sciences, 104(9), 3384-3389. Joncker, N. T., Fernandez, N. C., Treiner, E., Vivier, E., & Raulet, D. H. (2009). NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. The Journal of Immunology,182(8), 4572-4580. Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., ... & Mandelboim, O. (2006). Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nature immunology, 7(5), 517-523.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 29A1.4 antibody specifically reacts with CD335 (NKp46), a 46kDA natural cytotoxicity receptor family molecule. It is expressed in only NK and a rare subset of NK-like T cells, not including the CD1d-restricted NKT division. CD335 is active during NK lysis of pathogen-infected and tumor cells. The 29A1.4 in vitro activates NK cells, but does not deplete NK cells in vivo.
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

37412-60-25-datasheet.pdf

37412-60-25-safety-datasheet.pdf