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Anti-Mouse Notch3 APC

Anti-Mouse Notch3 APC

Item no.	73312-80-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies Flow Cytometry Primary Antibodies By Organ Skin Cancer
Type	Antibody
Format	APC
Applications	FC
Clone	HMN3-133
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Isotype	IgG
Conjugate/Tag	APC
Citations	Moriyama, Y., Sekine, C., Koyanagi, A., Koyama, N., Ogata, H., Chiba, S., ... & Yagita, H. (2008). Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice. International immunology, 20(6), 763-773. Bellavia, D., Checquolo, S., Campese, A. F., Felli, M. P., Gulino, A., & Screpanti, I. (2008). Notch3: from subtle structural differences to functional diversity. Oncogene, 27(38), 5092-5098. Shi, J., Fallahi, M., Luo, J. L., & Petrie, H. T. (2011). Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.Blood, 118(9), 2511-2519.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Stem Cell Research

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

73312-80-100-datasheet.pdf

73312-80-100-safety-datasheet.pdf