Anti-Mouse IL-1 beta SAFIRE Purified

Item no.	82212-25-500
Manufacturer	BioGems
Amount	500 ug
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Primary Antibodies
Type	Antibody
Format	SAFIRE (Functional)
Clone	B122
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Isotype	IgG
Citations	Hogquist, K. A., Nett, M. A., Sheehan, K. C., Pendleton, K. D., Schreiber, R. D., & Chaplin, D. D. (1991). Generation of monoclonal antibodies to murine IL-1 beta and demonstration of IL-1 in vivo. The Journal of immunology, 146(5), 1534-1540. Fei, R., Gott, K., Edwards, B., & Schuyler, M. (1995). Experimental hypersensitivity pneumonitis: in vitro effects of interleukin-2 and interferon-gamma. The Journal of laboratory and clinical medicine, 126(5), 485-494. Miller, B. E., Krasney, P. A., Gauvin, D. M., Holbrook, K. B., Koonz, D. J., Abruzzese, R. V., ... & Ator, M. A. (1995). Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme. The Journal of Immunology,154(3), 1331-1338.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The B122 monoclonal antibody specifically reacts with the precursor and mature secreted forms of mouse IL-1β and is cross-reactive with rat IL-1β. IL-1α and IL-1β are recognized by the same cell surface receptor but are generated from distinct genes. The B122 antibody is reported to neutralize the bioactivity of natural or recombinant IL-1β.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Innate Immunity
Format	SAFIRE (Functional)

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82212-25-500-datasheet.pdf

82212-25-500-safety-datasheet.pdf