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Anti-Mouse IL-12/IL-23 p40 PE

Anti-Mouse IL-12/IL-23 p40 PE

Item no.	83312-60-100
Manufacturer	BioGems
Amount	100 ug
Category	Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Primary Antibodies
Type	Antibody
Format	PE
Applications	FC
Clone	C17.8
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	PE
Citations	Wysocka, M., Kubin, M., Vieira, L. Q., Ozmen, L., Garotta, G., Scott, P., & Trinchieri, G. (1995). Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice. European journal of immunology, 25(3), 672-676. Cho, D., Lee, W. J., Halloran, P. J., Trinchieri, G., & Kim, Y. B. (1996). Enhancement of porcine natural killer cell activity by recombinant human and murine IL-12. Cellular immunology, 172(1), 29-34. D'Andrea, A., Rengaraju, M., Valiante, N. M., Chehimi, J., Kubin, M., Aste, M., ... & Nickbarg, E. (1992). Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. The Journal of experimental medicine, 176(5), 1387-1398.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Request Data Sheet

83312-60-100-datasheet.pdf

83312-60-100-safety-datasheet.pdf