« Back
Home /
Anti-Mouse NK1.1 (CD161) Purified

Anti-Mouse NK1.1 (CD161) Purified

Item no.	83712-20-100
Manufacturer	BioGems
Amount	100 ug
Category	Antibodies Flow Cytometry Immunoprecipitation Primary Antibodies
Type	Antibody
Format	Purified
Applications	FC, IP
Clone	PK136
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Koo, G. C., & PEPPARD, J. R. (1984). Establishment of monoclonal anti-Nk-1.1 antibody. Hybridoma, 3(3), 301-303. Carlyle, J. R., Martin, A., Mehra, A., Attisano, L., Tsui, F. W., & Zuniga-Pflücker, J. C. (1999). Mouse NKR-P1B, a novel NK1. 1 antigen with inhibitory function. The Journal of Immunology, 162(10), 5917-5923. Karlhofer, F. M., & Yokoyama, W. M. (1991). Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1. 1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. The Journal of Immunology, 146(10), 3662-3673.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family. Nk1.1 is an antigen encoded by the Klrb1c/NKR-P1C gene expressed by the natural killer cells of some selected strains of mice (C57BL, FVB/N, NZB) and encoded by the Klrb1b/NKR-P1B gene expressed on Swiss NIH and SJL mice. Pk136 binds to an epitope common to NKR-P1B and NKR-P1C. The Klrb1 is a family of type II transmembrane C-type lectin receptors. Klrb1c activates the NK-cell cytotoxicity, while Klrb1b inhibits it. PK136 is useful in defining the NK cells and the rare population of NK-T lymphocytes and specific cultured monocytes.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity
Format	Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

83712-20-100-datasheet.pdf

83712-20-100-safety-datasheet.pdf