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Anti-Mouse Fc epsilon Receptor I alpha (FceR1) PE

Anti-Mouse Fc epsilon Receptor I alpha (FceR1) PE

Item no.	84112-60-100
Manufacturer	BioGems
Amount	100 ug
Category	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Pancreatic Cancer
Type	Antibody
Format	PE
Applications	FC
Clone	41699
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Isotype	IgG
Conjugate/Tag	PE
Citations	Joncker, N. T., Fernandez, N. C., Treiner, E., Vivier, E., & Raulet, D. H. (2009). NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. The Journal of Immunology,182(8), 4572-4580. Obata, K., Mukai, K., Tsujimura, Y., Ishiwata, K., Kawano, Y., Minegishi, Y., ... & Karasuyama, H. (2007). Basophils are essential initiators of a novel type of chronic allergic inflammation. Blood, 110(3), 913-920. Arinobu, Y., Iwasaki, H., Gurish, M. F., Mizuno, S. I., Shigematsu, H., Ozawa, H., ... & Akashi, K. (2005). Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America, 102(50), 18105-18110.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The Mar-1 monoclonal antibody binds to the Fc ε Receptor I α subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells. The Fc ε Receptor I α subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Innate Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

84112-60-100-datasheet.pdf

84112-60-100-safety-datasheet.pdf