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Anti-Mouse B7-H4 SAFIRE Purified

Anti-Mouse B7-H4 SAFIRE Purified

Item no.	86612-25-50
Manufacturer	BioGems
Amount	50 ug
Category	Oncology Antibodies By Cell Type Carcinoma Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	188
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Citations	Yi, K. H., & Chen, L. (2009). Fine tuning the immune response through B7-H3 and B7-H4. Immunological reviews, 229(1), 145-151. Chen, Y., Yang, C., Xie, Z., Zou, L., Ruan, Z., Zhang, X., ... & Wu, Y. (2006). Expression of the novel co-stimulatory molecule B7-H4 by renal tubular epithelial cells. Kidney international, 70(12), 2092-2099. Kamimura, Y., Kobori, H., Piao, J., Hashiguchi, M., Matsumoto, K., Hirose, S., & Azuma, M. (2009). Possible involvement of soluble B7-H4 in T cell-mediated inflammatory immune responses. Biochemical and biophysical research communications, 389(2), 349-353.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 188 monoclonal antibody binds to mouse B7-H4, a newly discovered member of the B7 family involved with the negative regulation of T cell immunity. B7-H4 is a type I membrane glycoprotein also known as B7S1, B7X, and VCTN1. Its role in tumor progression may be to protect precancerous cells from the surveillance of the immune system. Further studies are being conducted to determine the exact B7-H4 ligand. It is reported that the H74 antibody binds to mouse B7-H4 transfected cells and not spleen cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ph7.2.
Preperation	The product should be stored undiluted at 4C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
Research Interest	Adaptive Immunity
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

86612-25-50-datasheet.pdf

86612-25-50-safety-datasheet.pdf