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Anti-Rat CD8b SAFIRE Purified

Anti-Rat CD8b SAFIRE Purified

Item no.	10113-25-500
Manufacturer	BioGems
Amount	500 ug
Category	Neuroscience Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies
Type	Antibody
Format	SAFIRE Purified
Applications	FC
Clone	341
Specific against	Rat (Rattus norvegicus)
Host	Rat
Isotype	IgG2b
Citations	Salem, M. L., & Hossain, M. S. (2000). In vivo acute depletion of CD8+ T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells. International journal of immunopharmacology, 22(9), 707-718. Kruisbeek, A. M. (1991). In Vivo Depletion of CD4 and CD8 Specific T Cells.Current protocols in immunology, 4-1. Davies, A., Kalb, S., Liang, B., Aldrich, C. J., Lemonnier, F. A., Jiang, H., ... & Soloski, M. J. (2003). A peptide from heat shock protein 60 is the dominant peptide bound to Qa-1 in the absence of the MHC class Ia leader sequence peptide Qdm. The Journal of Immunology, 170(10), 5027-5033.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 molecule. The alpha and beta chains of the CD8 molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that macrophages express CD8 alpha and beta chains for signal transduction. CD8 is an antigen co-receptor that interacts with MHC class I molecules on antigen-presenting cells.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity
Format	SAFIRE Purified

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

10113-25-500-datasheet.pdf

10113-25-500-safety-datasheet.pdf