Comparison

PPP1CB Polyclonal Antibody

Item no. BM-CAC08014-50ug
Manufacturer Biomatik
Amount 50 UG
Category
Type Antibody Polyclonal
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Serine/threonine-protein phosphatase PP1-beta catalytic subunit,PP-1B,PPP1CD,PPP1CB
Available
Shipping Temperature
Blue ice
Storage Conditions
Aliquot and store at -20°C. Minimize freezing and thawing.
Restrictions
For research use only. Not for diagnostic procedures.
Expiration
1 year
Purification
Protein G purified, >95%
Comments
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
Immunogen
Recombinant Human Serine/threonine-protein phosphatase PP1-beta catalytic subunit protein (2-327AA)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 UG
Available: In stock
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