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SOCS7 Polyclonal Antibody

SOCS7 Polyclonal Antibody

Manufacturer	Biomatik
Category	Metabolism Glucose Homeostasis Antibodies Western Blot ELISA Immunofluorescence Cardiovascular Research Thrombosis & Hemostasis Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Rat
Applications	WB, IF, ELISA
Amount	50ug
Host	Rabbit
Item no.	BM-CAC08197-50ug
Targets	SOCS7
eClass 6.1	32160702
eClass 9.0	32160702
Available
Immunogen	Recombinant Human Suppressor of cytokine signaling 7 protein (6-165AA)
Conjugate	Unconjugated
Alternative Names	Suppressor of cytokine signaling 7, SOCS-7, Nck, Ash and phospholipase C gamma-binding protein, Nck-associated protein 4, NAP-4, SOCS7, NAP4, SOCS6
UniProt ID	O14512
Purification	Protein G purified, >95%
Storage Instructions	Aliquot and store at -20C. Minimize freezing and thawing.
Expiry Date	1 year
Shipping Condition	Blue ice
Comment	Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 5/30/2024