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Mouse monoclonal antibody to human LIMK-1 [1A8]: IgG

Mouse monoclonal antibody to human LIMK-1 [1A8]: IgG

Item no.	M-844-50
Manufacturer	Biosensis
Amount	50ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot ELISA Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IHC, ELISA
Clone	1A8
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	LIMK1, LIMK, LIM domain kinase 1
Available
Sub category	Development-Stem Cells
products_extra_fields_value	LIMK-1A belongs to a small subfamily of LIM proteins with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 regulates actin filament dynamics. It phoshorylates and inactivates the actin binding/ depolymerising factor cofilin, consequently stabilising the actin cytoskeleton. It may also be involved in brain development. LIMK-1 localises to the cytoplasm and is highly expressed in both the adult and fetal nervous system. It is expressed to a lesser extent in heart and skeletal muscle. LIMK-1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. A
products_quantity	200
storage	After reconstitution keep aliquots at -20AC for higher stability or at 4AC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
purityisotype	Protein G purified immunoglobulin
formulation	Lyophilised from PBS pH 7.2
immunogen	Partial recombinant protein of human LIMK-1 (aa 548 to 648) with a GST tag.
crossreactivity	Human. Other species have not been tested.
conality	Mouse
specificity	Specificity has been confirmed by WB and direct ELISA against the antigen.
reconstitution	Reconstitute in 50 Aul of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 11/13/2025

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