Rabbit polyclonal antibody to human STAT3 (686-698): Affinity purified

STAT3 belongs to the STAT (signal transducers and activators of transcription) family of proteins. STAT proteins undergo tyrosine/serine phosphorylation in response to cytokines and growth factors. Phosphorylated STAT3 forms a homodimer or heterodimer with related family members such as STAT1. Phosphorylated STAT proteins are translocated to the nucleus where they act as transcription factors. STAT3 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas tissues.A Alternative splicing of the STAT3 gene gives rise to at least 2 isoforms.

At least 12 months after purchase at 2 - 4AC (lyophilized formulations).After reconstitution, aliquot and store at -20AC for a higher stability.Avoid freeze-thaw cycles

Lyophilised with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3

Human, mouse, rat, rabbit,

The specificity of this antibody has been confirmed by WB and IHC against the antigen.