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Mouse monoclonal antibody to Neurofilament Light [DA2]

Mouse monoclonal antibody to Neurofilament Light [DA2]

Item no.	M-1391-50
Manufacturer	Biosensis
Amount	50ul
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies Neurodegeneration Markers
Type	Antibody Monoclonal
Applications	WB, IHC, ICC
Clone	DA2
Specific against	other
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	NF-L, NEFL, NF68, Neurofilament light polypeptide, NFL
Available
Sub category	Development-Cell Markers
products_extra_fields_value	Neurofilaments are composed of three intermediate filament proteins: light (ca.68 kDa), medium (ca.160 kDa) and heavy (ca.200 kDa), which are involved in the maintenance of the neuronal caliber. Neurofilament light (NF68 or NF-L) is the most abundant of the three proteins.
products_quantity	200
storage	After reconstitution of lyophilised antibody, aliquot and store at -20AC for a higher stability. Avoid freeze-thaw cycles.
formulation	Lyophilised with 5% trehalose
immunogen	A preparation of enzymatically dephosphorylated pig neurofilaments including NF-L, NF-M and NF-H. Screening was by ELISA on the immungen followed by immunofluorescence microscopy. The epitope for this antibody is not in the N-terminus but its exact location is not known. It is thought to be somewhere within the central alpha helical "rod" region of the molecule.
crossreactivity	Hu, Rat, Ms, Fel, Bov, Por, Chk
conality	Mouse
specificity	Specifically recognizes the light neurofilament subunit NF-L (ca.68 kDa) in WB.
reconstitution	Reconstitute in sterile distilled water. Centrifuge to remove any insoluble material.
specificreferences	1. Felitsyn N. et al (2008) The heme precursor delta-aminolevulinate blocks peripheral myelin formation. J Neurochem. 2008 Sep, 106(5):2068-79.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 11/13/2025

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