Comparison

Mouse monoclonal antibody to the human Tyrosine kinase receptor type B [4D3-F10]: IgG

Item no. M-853-100
Manufacturer Biosensis
Amount 100ug
Category
Type Antibody Monoclonal
Applications WB, ELISA
Clone 4D3-F10
Specific against other
Host Mouse
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Similar products TrkB, NTRK2, BDNF/NT-3 growth factors receptor, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Trk-B, Tropomyosin-related kinase receptor, GP145-TrkB, TRKB
Available
Sub category
Neurotrophic Factor Receptors-Sensory Nervous System-Stem Cells-Diabetes & Obesity
products_extra_fields_value
Tyrosine kinase receptor type B (TrkB) is a member of the neurotrophic tyrosine receptor kinase family. It is a membrane-bound receptor and upon neurotrophin binding, it phosphorylates itself as well as MAPK pathways members. TrkB is the receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5, but not nerve growth factor (NGF). It is involved in the development and/or maintenance of the nervous system. It exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures.A It is a tran-membrane protein. There are 3 named isoforms produced by alternative splicing. Additional isoforms seem to exist. The different forms are differentially expressed in various cell types.
products_quantity
200
storage
After reconstitution keep aliquots at -20AC for higher stability or at 4AC with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
purityisotype
Protein G purified immunoglobulin
formulation
Lyophilised from PBS pH 7.2
immunogen
Recombinant protein of human Tyrosine kinase receptor type B (isoform TrkB-T1) with a GST tag.
crossreactivity
Human. Other species have not been tested.
conality
Mouse
specificity
Specificity has been confirmed by WB and direct ELISA against the antigen.
reconstitution
Reconstitute in 100 Aul of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
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