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Mouse monoclonal antibody to alpha actin (smooth muscle) [1A4]: IgG

Mouse monoclonal antibody to alpha actin (smooth muscle) [1A4]: IgG

Item no.	M-996-100
Manufacturer	Biosensis
Amount	100ug
Category	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Movement Immunohistochemistry Western Blot Primary Antibodies Cell Migration & Invasion By Organ Skin Cancer
Type	Antibody Monoclonal
Applications	WB, IHC
Clone	1A4
Specific against	other
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	ACTA2, ACTSA, ACTVS
Available
Sub category	Stem Cells
products_extra_fields_value	Actins are highly conserved proteins ubiquitously expressed in all eukaryotic cells. Three main groups of actin isoforms have been identified in vertebrates, alpha, beta and gamma. Alpha actins are found mainly in muscle tissues.
products_quantity	200
storage	At least 12 months after purchase at 2 - 4AC (lyophilized formulations). After reconstitution, aliquot and store at -20AC for a higher stability. Avoid freeze-thaw cycles.
purityisotype	IgG
formulation	Lyophilized from 1.2% sodium acetate, 2mg BSA, 0.01mg NaN3
immunogen	A synthetic peptide of 10 amino acids corresponding to the N-terminus of alpha smooth muscle actin. This antibody reacts only with alpha smooth muscle actin and does not react with actin from striated muscle (alpha-sarcomeric) and myocardium (alpha-myocardial). It also does not react with beta and gamma actins.
crossreactivity	Human, mouse, rat,
conality	Mouse
specificity	The specificity of this antibody has been confirmed by WB and IHC against the antigen.
reconstitution	Reconstitute in 1 ml of PBS to achieve an antibody concentration of 100 Aug/ml. Centrifuge to remove any insoluble material.
specificreferences	1. Pogribny IP et al (2013) Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury. FASEB J. 2013 Jun, 27(6):2233-43. 2. Sebastiani G et al (2011) Accelerated CCl4-induced liver fibrosis in Hjv-/- mice, associated with an oxidative burst and precocious profibrogenic gene expression. PLoS One. 2011, 6(9):e25138.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 11/13/2025

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