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Rabbit polyclonal antibody to Nicastrin, central region: IgG

Rabbit polyclonal antibody to Nicastrin, central region: IgG

Item no.	R-1685-500
Manufacturer	Biosensis
Amount	500ug
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Immunoprecipitation Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IP
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Sub category	Alzheimer's / Parkinson's
products_extra_fields_value	Nicastrin, a type 1 membrane glycoprotein, is an essential component of the gamma secretase complex which is critical for the cleavage of the amyloid precursor protein and other membrane proteins. Nicastrin is widely expressed in different tissue types. This antibody reacts with immature forms of Nicastrin. Detection of higher mol. wt. mature forms is likely to be blocked by glycosylation in this region of the protein.
products_quantity	200
storage	Short term storage at 2-8AC for one week. At -20AC as an undiluted liquid for up to 12 months.
formulation	Lyophilized
immunogen	A synthetic peptide (C-QGETFDYIGSSRMVYD) corresponding to human Nicastrin [331-346] in the central region conjugated via additional N-terminal Cys to Diphtheria toxoid.
conality	Rabbit
specificity	Confirmed by WB using peptide absorption.
reconstitution	Reconstitute in 500 AuL of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500ug

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Delivery expected until 11/13/2025

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