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MMP 17 (MT4-MMP) catalytic domain, His-tagged

MMP 17 (MT4-MMP) catalytic domain, His-tagged

Item no.	BTZ-30100403
Manufacturer	BioTeZ
Amount	200 ug/1 ml
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Conjugate/Tag	His
Protein Family	Matrix Metalloproteinases, matrixins
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Purity	80%
Product Subcategory	EC 3.4.24.-
Pathway and Disease	Among MMP17 related pathways are Matrix Metalloproteinases and Degradation of the extracellular matrix.
Description	MMP17 is a endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Applications Info	Degradation of extracellular Matrix, Screening and evaluation of MMP inhibitors, Antigen standard
Alternate Names	Membrane-Type 4 Matrix Metalloproteinase
Sequence	Q A P A P T K W N K R N L S W R V R T F P R D S P L G H D T V R A L M Y Y A L R V W S D I A P L N F H E V A G S T A D I Q I D L S K A D H N D G Y P F D G P G G T V A H A F F P G H H H T A G D T H F D D D E A W T F R S S D A H G M D L F A V A V H E F G H A I G L S H V A A A H S I M R P Y Y Q G P V G D P L R Y G L P Y E D K V R V W Q L Y G V R E S V S P T A Q P E E P P L E H H H H H H
Accession No	Q9ULZ9
Composition	50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2, 0.1% Triton X-100.
Storage	Store at -70C
Target Modification	No
Expression System	E.coli
Product Subtype	protein fragment
Active?	Yes
Tag	His-tagged
Gene ID	4326
Molecular Weight	24 kDa
Shipping Temp Min	dry ice
Product description long	The catalytic domain of human MT4-MMP is produced by tryptic activation of a recombinant soluble proform purified from E. coli periplasm.
Purification	Mentioned in the data sheet
Restrictions	For Research Use only.
NCBI Official Symbol	MMP17 (partial)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ug/1 ml

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Delivery expected until 10/30/2025

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