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MMP 1 (Interstitial Collagenase)

MMP 1 (Interstitial Collagenase)

Item no.	BTZ-30101002
Manufacturer	BioTeZ
Amount	10 ug/200ul
Category	Neuroscience Neuroinflammation Peptides & Proteins Cell Biology Cell Stainings ECM Native Proteins
Type	Proteins Native
Format	Liquid
Specific against	Human (Homo sapiens)
Protein Family	Matrix Metalloproteinases, matrixins
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Purity	>90%
Product Subcategory	EC 3.4.24.7
Pathway and Disease	Diseases associated with MMP1 include Epidermolysis Bullosa Dystrophica, Ar and Pulmonary Disease, Chronic Obstructive. Among its related pathways are Pathways in cancer and PPAR signaling pathway.
Description	MMP1 cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tats mediated neurotoxicity.
Applications Info	Degaradation of extracellular Matrix, Screening and evaluation of MMP inhibitors, Antigen standard
Alternate Names	Matrix Metalloproteinase 1, Fibroblast Collagenase
Sequence	MHSFPPLLLLLFWGVVSHSFPATLETQEQDVDLVQ KYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEF FGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEG NPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQL WSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFD GPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREY NLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGD VQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDS KLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELN FISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWA VQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEEN TGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFP GIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRIL TLQKANSWFNCRKN
Accession No	P03956
Composition	50 mM Tris/HCl, pH 7.0, 300 mM NaCl, 5 mM CaCl2, 1 uM ZnCl2, 0.05% NaN3, 0.05% Brij 35.
Storage	Store at -70C
Target Modification	No
Expression System	Human Fibroblast
Product Subtype	full length
Active?	Yes
Tag	untagged
Gene ID	4312
Molecular Weight	52-56 kDa
Shipping Temp Min	dry ice
Product description long	Human MMP1 is isolated from human fibroblasts.
Purification	Mentioned in the data sheet
Restrictions	For Research Use only.
NCBI Official Symbol	MMP1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug/200ul

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Delivery expected until 10/30/2025

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