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Anti-Bcl-2 (phospho-T69) Antibody

Anti-Bcl-2 (phospho-T69) Antibody

Item no.	BOS-A00040T69
Manufacturer	Boster
Amount	100 ul
Category	Oncology By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Immunohistochemistry Autophagy By Organ Colorectal Cancer Testicular & Prostate Cancer
Format	Liquid
Applications	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Apoptosis regulator Bcl-2,BCL2
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	26266 MW
Clonality	Polyclonal
Application Details	IHC: 1:50-1:200
Gene Name	BCL2
Gene Full Name	Apoptosis regulator Bcl-2
Immunogen	Synthetic phosphopeptide derived from human Bcl-2 around the phosphorylation site of Threonine 69.
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Apoptosis regulator Bcl-2
Protein Function	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Subcellular Localization	Mitochondrion outer membrane
Description	Boster Bio Anti-Bcl-2 (phospho-T69) Antibody catalog # A00040T69. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in a variety of tissues.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00040T69-datasheet.pdf

BOS-A00040T69-safety-datasheet.pdf