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Anti-VEGF Antibody

Anti-VEGF Antibody

Item no.	BOS-A00045-4
Manufacturer	Boster
Amount	100 ul
Category	Oncology By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Adenocarcinoma Flow Cytometry Immunohistochemistry Immunofluorescence Immunocytochemistry By Organ Bladder Cancer Immunochemistry
Format	Liquid
Applications	FC, IF, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Vascular endothelial growth factor A,VEGF-A,Vascular permeability factor,VPF,VEGFA,VEGF
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	27042 MW
Clonality	Polyclonal
Application Details	ICC/IF: 1:50-1:200 IHC: 1:50-1:200 FC: 1:50-1:100
Gene Name	VEGFA
Gene Full Name	Vascular endothelial growth factor A
Immunogen	recombinant protein
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	ProA affinity purified
Concentration	1 mg/ml
Protein Name	Vascular endothelial growth factor A
Protein Function	Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).
Subcellular Localization	Secreted
Description	Boster Bio Anti-VEGF Antibody catalog # A00045-4. Tested in ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed. A higher level expression seen in pituitary tumors as compared to the pituitary gland.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00045-4-datasheet.pdf

BOS-A00045-4-safety-datasheet.pdf