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Anti-Fas (CD95) Antibody

Anti-Fas (CD95) Antibody

Item no.	BOS-A00055-1
Manufacturer	Boster
Amount	100 ul
Category	Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Immunochemistry
Format	Liquid
Applications	WB, FC, IF, IHC, ICC
Specific against	Human (Homo sapiens)
Host	Rabbit
Alias	Tumor necrosis factor receptor superfamily member 6,Apo-1 antigen,Apoptosis-mediating surface antigen FAS,FASLG receptor,CD95,FAS,APT1,FAS1,TNFRSF6
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	37732 MW
Clonality	Polyclonal
Application Details	WB: 1:500-1:1, 000 ICC: 1:50-1:200 IHC: 1:50-1:200 FC: 1:50-1:100
Gene Name	FAS
Gene Full Name	Tumor necrosis factor receptor superfamily member 6
Immunogen	recombinant protein
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	ProA affinity purified
Concentration	1 mg/ml
Protein Name	Tumor necrosis factor receptor superfamily member 6
Protein Function	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Subcellular Localization	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Description	Boster Bio Anti-Fas (CD95) Antibody catalog # A00055-1. Tested in WB, ICC/IF, IHC, Flow Cytometry applications. This antibody reacts with Human.
Tissue Specificity	Isoform 1 and isoform 6 are expressed at equal levels in resting peripheral blood mononuclear cells. After activation there is an increase in isoform 1 and decrease in the levels of isoform 6.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00055-1-datasheet.pdf

BOS-A00055-1-safety-datasheet.pdf