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Anti-Smad2 (Phospho-S255) Antibody

Anti-Smad2 (Phospho-S255) Antibody

Item no.	BOS-A00090S255
Manufacturer	Boster
Amount	100 ul
Category	Neuroscience Neural Lineage Markers Immunohistochemistry Immunoprecipitation Western Blot Neurodegeneration Markers
Format	Liquid
Applications	WB, IP, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Mothers against decapentaplegic homolog 2,MAD homolog 2,Mothers against DPP homolog 2,JV18-1,Mad-related protein 2,hMAD-2,SMAD family member 2,SMAD 2,Smad2,hSMAD2,SMAD2,MADH2,MADR2
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	52306 MW
Clonality	Polyclonal
Application Details	WB: 1:1, 000 IHC: 1:50-1:200
Gene Name	SMAD2
Gene Full Name	Mothers against decapentaplegic homolog 2
Immunogen	Synthetic phospho-peptide corresponding to residues surrounding Ser255 of human Smad2.
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	ProA affinity purified
Concentration	1 mg/ml
Protein Name	Mothers against decapentaplegic homolog 2
Protein Function	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Subcellular Localization	Cytoplasm
Description	Boster Bio Anti-Smad2 (Phospho-S255) Antibody catalog # A00090S255. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00090S255-datasheet.pdf

BOS-A00090S255-safety-datasheet.pdf