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Anti-Keap1 Antibody

Anti-Keap1 Antibody

Item no.	BOS-A00514-2
Manufacturer	Boster
Amount	100 ul
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Kelch-like ECH-associated protein 1,Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19,KEAP1,INRF2,KIAA0132,KLHL19
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	69666 MW
Clonality	Polyclonal
Application Details	WB 1:500-1:2000 IHC: 1:100-300 ELISA 1:20000 IF 1:50-200
Gene Name	KEAP1
Gene Full Name	Kelch-like ECH-associated protein 1
Immunogen	The antiserum was produced against synthesized peptide derived from the Internal region of human KEAP1. AA range:411-460
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Protein Name	Kelch-like ECH-associated protein 1
Protein Function	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Subcellular Localization	Cytoplasm. Nucleus. Shuttles between cytoplasm and nucleus.
Description	Boster Bio Anti-Keap1 Antibody catalog # A00514-2. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Broadly expressed, with highest levels in skeletal muscle.
Short Description	Boster Bio Anti-Keap1 Antibody catalog # A00514-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A00514-2-datasheet.pdf

BOS-A00514-2-safety-datasheet.pdf