Item no. |
BOS-A00897-Dylight550 |
Manufacturer |
Boster
|
Amount |
100 ug |
Format |
Lyophilized |
Applications |
WB |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus) |
Host |
Rabbit |
Isotype |
IgG |
Citations |
1. Gromoll, J., Ried, T., Holtgreve-Grez, H., Nieschlag, E., Gudermann, T. Localization of the human FSH receptor to chromosome 2p21 using a genomic probe comprising exon 10. J. Molec. Endocr. 12: 265-271, 1994. |
Alias |
Follicle-stimulating hormone receptor;FSH-R;Follitropin receptor;FSHR;LGR1; |
Available |
|
Manufacturer - Category |
Primary Antibodies |
Manufacturer - Isotype |
Rabbit IgG |
Manufacturer - Conjugate / Tag |
Dylight550 |
Storage Conditions |
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. |
Observed Molecular Weight |
78 kDa |
Calculated Molecular weight |
78265 MW |
Clonality |
Polyclonal |
Application Details |
Western blot, 0.1-0.5μg/ml, Human, Mouse |
Manufacturer - Gene Name |
FSHR |
Gene Full Name |
Follicle-stimulating hormone receptor |
Manufacturer - Specificity |
No cross reactivity with other proteins. |
Background |
The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). This FSHR gene is mapped to chromosome 2p21 by fluorescence in situ hybridization. The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants. |
Immunogen |
A synthetic peptide corresponding to a sequence in the middle region of human FSH Receptor, identical to the related mouse and rat sequences. |
Contents |
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg NaN3. |
Purification |
Immunogen affinity purified. |
Reconstitution |
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml. |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Manufacturer - Research Category |
Endocrine System, G Protein Signaling, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway |
Protein Name |
Follicle-stimulating hormone receptor(FSH-R) |
Protein Function |
Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Subcellular Localization |
Cell membrane; Multi-pass membrane protein. |
Description |
Boster Bio Anti-FSH Receptor/FSHR Antibody Picoband® catalog # A00897. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. |
Tissue Specificity |
Sertoli cells and ovarian granulosa cells. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.