Anti-FAS-L FASLG Antibody

Primary Antibodies

31485 MW

WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:40000

Tumor necrosis factor ligand superfamily member 6

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

1 mg/ml

Cytokine that binds to TNFRSF6/FAS, a receptor that
transduces the apoptotic signal into cells (PubMed:26334989,
PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis,
natural killer cell-mediated apoptosis and in T-cell development
(PubMed:9228058, PubMed:7528780, PubMed:9427603). Initiates
fratricidal/suicidal activation-induced cell death (AICD) in
antigen-activated T-cells contributing to the termination of
immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis
has also a role in the induction of peripheral tolerance (By
similarity). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks
apoptosis (PubMed:27806260).

Boster Bio Anti-FAS-L FASLG Antibody catalog # A00925-1. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Pig.

Tumor necrosis factor ligand superfamily member 6, Apoptosis antigen ligand, APTL, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL, CD178, Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form, Receptor-binding FasL ectodomain, Soluble Fas ligand, sFasL, ADAM10-processed FasL form, APL, FasL intracellular domain, FasL ICD, SPPL2A-processed FasL form, SPA, FASLG, APT1LG1, CD95L, FASL, TNFSF6