Anti-Bone marrow stromal antigen 2 Bst2 Antibody

Primary Antibodies

19152 MW

Bst2 antibody can be used for detection of Bst2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Bone marrow stromal cell antigen 2

Bst2 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of the mouse Bst2. The immunogen is located within amino acids 60 - 110 of Bst2.

Bst2 Antibody is affinity chromatography purified via peptide column.

Infectious Diseases

IFN-induced antiviral host restriction factor which
efficiently blocks the release of diverse mammalian enveloped
viruses by directly tethering nascent virions to the membranes of
infected cells. Acts as a direct physical tether, holding virions
to the cell membrane and linking virions to each other. The
tethered virions can be internalized by endocytosis and
subsequently degraded or they can remain on the cell surface. In
either case, their spread as cell-free virions is restricted. Its
target viruses belong to diverse families, including retroviridae:
human immunodeficiency virus type 1 (HIV-1), mouse mammary tumor
virus (MMTV) and murine leukemia virus (MLV), filoviridae: ebola
virus (EBOV), arenaviridae: lassa virus (LASV), and rhabdoviridae:
vesicular stomatitis virus (VSV). Can inhibit cell surface
proteolytic activity of MMP14 causing decreased activation of
MMP15 which results in inhibition of cell growth and migration.
Can stimulate signaling by LILRA4/ILT7 and consequently provide
negative feedback to the production of IFN by plasmacytoid
dendritic cells in response to viral infection. Plays a role in
the organization of the subapical actin cytoskeleton in polarized
epithelial cells.

Boster Bio Anti-Bone marrow stromal antigen 2 Bst2 Antibody (Catalog # A00934). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Rat