Anti-TBR2/Eomes Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

32462 MW

Western blot, 0.1-0.5μg/ml

ELISA, 0.1-0.5μg/ml

eomesodermin

Eomesodermin also known as T-box brain protein 2 (Tbr2) is a protein that in humans is encoded by the EOMES gene. This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.

Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05 mg NaN₃.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Cell Type Marker, 2339, Developmental Biology, Epigenetics and Nuclear Signaling, Germ Cell Markers, Germline Stem Cells, Intracellular, Lineage Specification, Neural Signal Transduction, Neural Stem Cells, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Reproduction, Stem Cells

Nucleus.

Expressed in CD8+ T-cells.