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Anti-IKB Alpha NFKBIA Antibody

Anti-IKB Alpha NFKBIA Antibody

Item no.	BOS-A01139
Manufacturer	Boster
Amount	100 ul
Category	Metabolism Cholesterol & Lipid Metabolism Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Immunochemistry
Format	Liquid
Applications	WB, IF, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	NF-kappa-B inhibitor alpha,I-kappa-B-alpha,IkB-alpha,IkappaBalpha,Major histocompatibility complex enhancer-binding protein MAD3,NFKBIA,IKBA,MAD3,NFKBI
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	35609 MW
Clonality	Polyclonal
Application Details	WB: 1:1, 000-1:5, 000 ICC: 1:50-1:200 IHC: 1:50-1:200
Gene Name	NFKBIA
Gene Full Name	NF-kappa-B inhibitor alpha
Immunogen	recombinant protein
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	ProA affinity purified
Concentration	1 mg/ml
Protein Name	NF-kappa-B inhibitor alpha
Protein Function	Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Subcellular Localization	Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Description	Boster Bio Anti-IKB Alpha NFKBIA Antibody catalog # A01139. Tested in WB, ICC/IF, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A01139-datasheet.pdf

BOS-A01139-safety-datasheet.pdf