Anti-PKM2 Antibody

Primary Antibodies

57937 MW

WB: 1:500-1:2000
IHC/IF: 1:50-1:200
IP/RIP: 1:50-1:200

Pyruvate kinase PKM

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Glycolytic enzyme that catalyzes the transfer of a
phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating
ATP. Stimulates POU5F1-mediated transcriptional activation. Plays
a general role in caspase independent cell death of tumor cells.
The ratio between the highly active tetrameric form and nearly
inactive dimeric form determines whether glucose carbons are
channeled to biosynthetic processes or used for glycolytic ATP
production. The transition between the 2 forms contributes to the
control of glycolysis and is important for tumor cell
proliferation and survival.

Boster Bio Anti-PKM2 Antibody catalog # A01173-1. Tested in WB, IHC, IF, IP, RIP applications. This antibody reacts with Human, Mouse, Rat.

Pyruvate kinase PKM, 2.7.1.40, Cytosolic thyroid hormone-binding protein, CTHBP, Opa-interacting protein 3, OIP-3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3, PKM2