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Anti-Phospho-Bim (S59) BCL2L11 Antibody

Anti-Phospho-Bim (S59) BCL2L11 Antibody

Item no.	BOS-A01552S59
Manufacturer	Boster
Amount	100 ul
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Immunohistochemistry ELISA Immunofluorescence Autophagy Immunostaining
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Alias	Bcl-2-like protein 11,Bcl2-L-11,Bcl2-interacting mediator of cell death,BCL2L11,BIM
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	22171 MW
Clonality	Polyclonal
Application Details	IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200
Gene Name	BCL2L11
Gene Full Name	Bcl-2-like protein 11
Immunogen	The antiserum was produced against synthesized peptide derived from human BIM around the phosphorylation site of Ser59. AA range:31-80
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Protein Name	Bcl-2-like protein 11
Protein Function	Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
Subcellular Localization	Endomembrane system; Peripheral membrane protein. Associated with intracytoplasmic membranes.
Description	Boster Bio Anti-Phospho-Bim (S59) BCL2L11 Antibody catalog # A01552S59. Tested in IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are widely expressed with tissue- specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney.
Short Description	Boster Bio Anti-Phospho-Bim (S59) BCL2L11 Antibody catalog # A01552S59. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-A01552S59-datasheet.pdf

BOS-A01552S59-safety-datasheet.pdf